Crohn's disease

 

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Random blog day boo yah. As you should know Fridays is random blog day were we talk anything and everything and pretty much run with it. Today's blog is on Crohn's Disease.

Crohn's disease is a type of inflammatory bowel disease (IBN) that can affect any part of the gastrointestinal tract. Common symptoms include abdominal pain, Diarrhea, fever, abdominal distension and weight loss. Other symptoms include anaemia, skin rashes and arthritis as well as fatigue and eye inflammation. The skin rashes could be due to infection as well as pyoderma, gangrenosum or erythema nodosum. Plus Bowl Obstructions could also occur as a complication of Chronic inflammation, and those with the disease are at a much greater risk of colon cancer and small bowl cancer.

Whilst what causes Crohn's disease (CD) is unknown, its believed that environment combined with immune and bacterial factors in those who are genetically susceptible have it. Whilst Crohn's is an immune related inflammatory disorder its not necessarily an autoimmune disease. Whilst the underlying problem isn't clear, it could be an immunodeficiency state. Unfortunately there is no current known cure for Crohn's (at the time of writing this blog), however there are treatment options which intent to help with symptoms, maintain remission and prevent relapse.

Crohn's disease affects about 3.2 people per 1,000 people in Europe and North America, It's less common in Asia and Africa though it has historically been more common in the developed world. Rates have been increasing since the 1970's and since 2015 inflammatory bowl disease has resulted in 47,400 deaths. Those with Crohn's disease have a slightly reduced life expectancy. Whilst Crohn's can start at any age it often starts in adolescence and young adulthood, with men and woman being effected equally.

The gastroenterologist Burrill Bernard Crohn is the man the disease is named after, he alongside Leon Ginzburg and Gordon D. Oppenheimer worked together in 1932 at New York's Mount Sinai Hospital and ended up describing a series of people with inflammation of the terminal ileum of the small intestine. The decision to name the disease after Crohn remains somewhat controversial as in his memoir Crohn describes his original investigation of the disease though Ginzburg provided strong evidence that both he (Ginzburg) and Oppenheimer were the first to study it,

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THE WEBSITE BIBLIOGRAPHY:

https://www.mayoclinic.org/diseases-conditions/crohns-disease/symptoms-causes/syc-20353304

https://www.nhs.uk/conditions/crohns-disease/

https://en.wikipedia.org/wiki/Crohn%27s_disease

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